Designing the Impossible: AI, Quantum Mechanics, and the Future of Materials | The Pair Program Ep95

Designing the Impossible: AI, Quantum Mechanics, and the Future of Materials | The Pair Program Ep95

In this episode of The Pair Program, we’re joined by Joseph Krause, Co-Founder and CEO of Radical AI, and Nathan Doctor, Founder and Managing Partner of Infinite Capital, for a conversation on the future of AI-driven scientific discovery and the rise of physical AI. From autonomous labs and materials science to robotics, semiconductors, and frontier tech investing, the discussion explores how breakthroughs in the physical world could define the next era of innovation.

What the conversation explores:

• Why the traditional scientific process is too slow for modern innovation
• How self-driving labs could transform materials discovery
• The importance of failed experiments and “messy data” in AI systems
• Why materials science may unlock the next major technological breakthroughs
• The growing intersection of AI, robotics, hardware, and the physical world
• How founders and investors think about long-term, world-changing innovation

About Joseph Krause:

Joseph is the co-founder and CEO of Radical AI, a company building autonomous research systems to accelerate breakthroughs in materials science. His background includes military research, semiconductor innovation, and deep tech investing through roles at Army DEVCOM and AlleyCorp. Joseph is focused on using AI to reshape how scientific and industrial innovation happens at scale.

About Nathan Doctor:

Nathan is the Founder and Managing Partner of Infinite Capital, focused on investing in emerging technologies across AI, aerospace, autonomy, and decentralized systems. Before Infinite, he founded Codewars and Qualified, platforms centered on developer education and technical assessment.

This episode is supported by Defense Unicorns

Defense Unicorns builds platform technologies that help deliver mission-critical capabilities faster and more reliably. Their open architecture approach enables secure, scalable systems without vendor lock, creating flexibility across the software ecosystem. Backed by a team of engineers, innovators, and veterans, they bring deep experience across defense and federal tech.

Get in touch at hello@defenseunicorns.com

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